Actively Enrolling Clinical Trials

Acute Coronary Syndrome

A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome (LIBREXIA-ACS)

Atrial Fibrillation

A Study of Milvexian Versus Apixaban in Participants With Atrial Fibrillation (LIBREXIA-AF)

Cardiovascular Disease

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

The African American Heart Study

REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood Vessels (REDEFINE 3)

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Renal Function in Adults Living With Obesity (TRIUMPH-OUTCOMES)

Lp(a) Lowering Study of Pelacarsen (TQJ230) in US Black/​African American and Hispanic Participants With Elevated Lp(a) and Established ASCVD

Heart Failure

A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation (ATHENA)

A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation (HERMES)

A Study to Test Whether BI 690517 in Combination With Empagliflozin Helps People With Heart Failure (EASI-HF)

Hyperlipidemia
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A Study of Olezarsen (ISIS 678354) Administered to Participants With Severe Hypertriglyceridemia (CORE-2)

Phase 3 Study of Plozasiran in Adults With Hypertriglyceridemia (MUIR-3)

Study of Plozasiran (ARO-APOC3) in Adults With Severe Hypertriglyceridemia (SHASTA-3)

Lp(a) Lowering Study of Pelacarsen (TQJ230) in US Black/​African American and Hispanic Participants With Elevated Lp(a) and Established ASCVD
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Obesity

A Study of Retatrutide (LY3437943) in Participants With Obesity and Cardiovascular Disease (TRIUMPH-3)